Welcome message

The Summer School on Pharmaceutical Analysis (SSPA) addresses the most advanced analytical methodologies that can be employed to support the drug discovery process from the early phases up to the manufacturing quality control. Indeed, the ultimate goal of a drug discovery program is to generate a candidate drug compound that, besides being active and selective in vitro on the isolated target, is safe and efficacious in humans. In order to develop such a compound, many aspects including affinity, activity, selectivity, physico-chemical properties, pharmacokinetics, pharmacodinamics and stability must be optimized. The definition of these criteria involves the availability and knowledge of appropriate analytical methodologies.

SSPA is therefore addressed to PhD students, young scientists, and professionals with a different scientific background, working in the field of drug discovery, who would like to enlarge their knowledge on the critical aspects to be taken into consideration when developing a new drug and on the analytical methodologies that can be applied to investigate such aspects.

Each SSPA edition is focused on a specific aspect/phase of the drug discovery process. However, a three-year school program is defined by the SSPA scientific board every three years, so that applicants can decide to attend the whole cycle or choose in advance editions which better fulfill their scientific or professional interests.

In the 2022 edition, SSPA will focus on Drug development: bioanalytical aspects and will feature the following main subjects:
The role of bioanalysis in drug development
Regulatory aspects
Bioanalytical sample preparation and method development
Pre-study and in-study method validation
Analysis of clinical samples and associated problems
Bioanalytical approaches for the analysis of peptides, oligonucleotides and antibody drug conjugates
Drug analysis in biological matrices using capillary electrophoresis
Metabolomics in drug development
Metabolites in safety testing (MIST): metabolites identification in humans
Quantitative whole-body autoradiography (QWBA) and radiolabelled mass-balance
Bioanalytical Data Management

Lectures will be delivered by recognized experts from the academic and industrial sectors. A list of confirmed lecturers is available at the section “meet our speakers”. The School social activities are planned to promote networking and favour interactivity between participants and lecturers. To maximize these aspects the number of participants in presence is limited to 80.

Official school language is English.

We are looking forward to welcoming you at the 2022 edition of SSPA in Rimini.

Manuela Bartolini
Chair of SSPA
Department of Pharmacy and Biotechnology, Alma Mater Studiorum University of Bologna

The Summer School on Pharmaceutical Analysis (SSPA) is organized by the Divisione di Chimica Farmaceutica, Società Chimica Italiana (Division of Medicinal Chemistry, Italian Chemical Society) and sponsored by the European Federation for Medicinal Chemistry and Chemical Biology (EFMC).

Location

Rimini (IT)

Date

21-23 September 2022

Speakers

14 Drug Discovery Professionals

Tickets

80 Students (+ virtual ticket)

SSPA 2022

Sept 21, 2022 - Sept 23, 2022

Registration

Program

A preliminary tabular program can be downloaded here (Printer friendly version).

The role of bioanalysis in drug development: present and future challenges

Union Chimique Belge (UCB), Brussels, Belgium

The regulated environment for bioanalysis (GLP and GCLP)

Aptuit, an Evotec Company, Verona, Italy

Abstract

Bioanalytical sample preparation

Merck R.B.M, Ivrea, Italy

Abstract

Bioanalytical method development and pre-study validation

Menarini Ricerche S.p.A. Italy

Abstract

Bioanalytical method development and pre-study validation

Accelera S.r.l, Nerviano, Italy

Abstract

11.00-11.20   Coffee break

Analysis of clinical samples and associated problems

Aptuit, an Evotec Company, Verona, Italy

Abstract

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LC-MS and HRMS for bioanalysis of peptides

Waters Italy

Abstract

Bioanalytical LC-MS methods to support analysis of oligonucleotides

Roche Ltd, Basel Switzerland

Abstract

15.30-15.50   Coffee break

Bioanalytical LC-MS methods to support analysis of Antibody Drug Conjugates

Merck R.B.M, Colleretto Giacosa, Italy

Abstract

Drug analysis in biological matrices using capillary electrophoresis

University of Verona, Verona, Italy

Metabolomics in drug development

Centre of Metabolomics and Bioanalysis (CEMBIO), Universidad San Pablo CEU, Madrid, Spain

Abstract

MIST: metabolites identification in human and comparison with preclinical species

Aptuit (Verona) Srl, an Evotec Company

Abstract

11.00-11.20   Coffee break

L
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C
H

T
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M
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Quantitative whole-body autoradiography (QWBA) and radiolabelled mass-balance

Accelera S.r.l, Nerviano, Italy

Abstract

Bioanalytical Data Management

LabWare Italy

Abstract

Location

The SSPA2022 is housed in Campus di Rimini, aula Briolini, Palazzo Ruffi-Briolini, Corso d’Augusto 237, Rimini. Venue location is mapped here below. The school venue is conveniently located at a walking distance from the rail station and in Rimini city center.

By car

From North: A1 Motorway Milan – Bologna, then A14 Motorway Bologna – Rimini
From South: A14 Motorway Bari – Rimini
Exit: Rimini Sud (for Rimini centre)

By train

Rimini is well connected by train to all the main cities in central and northern Italy. High speed trains connect Rimini to Bologna (1 h), Milan (2.5 h), Florence (2 h), Ancona (1 h) and Rome (4 h) several times a day.
Main railway station: Piazzale Cesare Battisti
Tickets can be bought on-line through the Italian railway website.

By plane

The city airport (‘Federico Fellini’ International Airport) is located in Miramare di Rimini.
Federico Fellini International airport in Rimini Federico Fellini International www.riminiairport.com
Closest Internationl airport is the Bologna International airport www.bologna-airport.it<

Meet Our Speakers

Alessandra Ariaudo

Alessandra Ariaudo
 

Merck R.B.M, Ivrea, Italy
 


She is a Medical Biotechnologist with a specialization in Virology and Microbiology obtained at the University of Turin. She worked for 7 years in the Clinical Pharmacology Laboratory of the Amedeo di Savoia Hospital, where she developed and validated chromatographic methods using UHPLC and HPLC instruments applied in pharmacokinetic studies for the analysis of several drugs and small molecules in different biological matrix. In 2017 she joined Merck company in Ivrea where she worked first in the LC-MS laboratory and from 2019 in the Formulation department laboratory, conducting GLP studies for the preparation and HPLC analysis of formulates for the in-vivo studies.

Coral Barbas

Coral Barbas
 

Universidad San Pablo CEU, Madrid, Spain
 


She is the author of more than 350 papers, with current research interests in all the steps of multiplatform metabolomics (GC-MS, LC-MS and CE-MS) in different pathophysiological situations and with different biological samples.

Chiara Baroglio

Chiara Baroglio
 

Accelera S.r.l, Nerviano, Italy
 


She is Head of Bioanalysis (small molecules) at Accelera srl since 2017. She is also core member of the European Bioanalytical Forum since 2016. She received her MSc degree in Biology and then she specialized in Biotechnology Applications at the University of Torino (Italy). In 2008 she joined Accelera srl, (NMS group) a contract research organization that provides drug development services to biotech, pharmaceutical companies and non-profit organizations at a global level. She has built expertise in providing LC-MS/MS bioanalytical support to preclinical and clinical studies conducted under GLP/GCP guidelines. Between 1999-2008 she worked as application specialist in Applied Biosystems, a private company operating in the life science field. Her main task was to deliver training courses on chromatography and mass spectrometry in southern Europe

Ellenia Bordini

Ellenia Bordini
 

Aptuit (Verona) Srl, an Evotec Company
 


She has got her Master’s Degree in Chemistry and Pharmaceutical Technology at the University of Padua and spent more than 19 years working in metabolite profiling field. During her career she worked for GSK, APTUIT, and she is actually a Research Expert for the ADMET & Bioanalitycal Sciences department. Ellenia has an extensive knowledge and background in the structural elucidation of metabolites in several biological matrices, generated from in vitro and/or in vivo studies conducted with or without radio-labelled drugs, by using liquid chromatography coupled with high resolution mass spectrometry. She is accountable for the scientific supervision of the metabolite identification activities and, in particular, for the metabolites in safety testing (MIST) strategy to evaluate human metabolism during clinical trials.

Luca Ferrari

Luca Ferrari
 

Roche Ltd, Basel Switzerland
 


He is Head of Small Molecule Bioanalytical Sciences at F. Hoffmann-La Roche (Basel, Switzerland) since 2013. He received his MSc Degree in Chemistry from the University of Padova in 1992. Before joining F. Hoffmann-La Roche, he spent seventeen years at GlaxoSmithKline where he held roles of increasing responsibility and became Head of Bioanalysis at the Italian R&D Site in 2001. In 2010 he joined Aptuit Verona S.r.l. as Head of Bioanalysis. He possesses an excellent understanding of LC-MS, bioanalytical method development and validation, GxPs and current global bioanalytical guidance. He is author of several scientific papers and speaker at numerous conferences.

Alessandro Greco

Alessandro Greco
 

Aptuit (Verona) Srl, an Evotec Company
 


He is Vice President at the ADMET & Bioanalytical Sciences Laboratory of Aptuit (Evotec company) in Verona (Italy) and he is also a member of European Bioanalytical Forum. Alessandro obtained his M.Sc. in Chemistry at the University La Sapienza in Rome. About twenty years of experience in the bioanalytical field with particular focus on liquid chromatography and mass spectrometry. He is responsible to coordinate and manage ADMET, LC-MS and Immunoassay laboratories. He is involved in the coordination of regulated bioanalytical activities supporting preclinical and clinical studies and project teams. Prior to joining Evotec, Alessandro worked as Team Leader in the Bioanalytical Laboratory at GlaxoSmithKline in Verona (Italy).

Sara Meli

Sara Meli
 

Accelera S.r.l, Nerviano, Italy
 


She graduated in Biology applied to the biomedical research at the university of Varese - Insubria, with a thesis in neuro-psychopharmacology. She joined Accelera S.r.l (NMS Group) in 2011, to conduct her thesis for the Master in Pharmacy and Oncological Pharmacology. From 2013 she works in Accelera Drug Disposition laboratory taking responsibility of regulated and non-regulated ADME studies, to support both discovery and development projects. She was mainly involved in in vivo activities with radiolabeled drugs like pharmacokinetics, excretion and tissue distribution studies, developing a specific expertise in the field of autoradiography technique (WBA).

Federico Pastori

Federico Pastori
 

LabWare Italy
 


He is Certified Consultant of LabWare in Verona (Italy). Federico obtained his M.Sc. in Chemistry at the University La Sapienza in Rome. He has about twenty years of experience, as Senior Study Director and Expert of Mass Spectrometry, in the bioanalytical field with a particular love for micro liquid chromatography coupled with high resolution MS, computerized system validation and laboratory data management in RTC (Rome) and then in ERBC (Rome). He was responsible for new method development for metabolism and drug-drug interaction services. He then decided to dedicate this new working experience to the LabWare LIMS configuration and implementation in different analytical laboratories extending his knowledge of the analytical processes.

Federico Riccardi Sirtori

Federico Riccardi Sirtori

Merck R.B.M, Colleretto Giacosa, Italy
 


He is a pharmaceutical chemist with strong competence in mass spectrometry with more than 20 years of experience in LC-MS and GC-MS techniques applied to small molecule and biopolymer (DNA, protein, antibodies). He holds a Laurea degree in organic chemistry and a Ph.D. in pharmaceutical chemistry from Milan University. Federico is currently working in Merck KGaA as Head of NBE-DMPK Innovative Bioanalytics. The department is focused on supporting NBE projects including the development and validation of new bioanalytical methods used to support preclinical studies (PK/TK). He was the author of more than 20 scientific publications.

Chiara Rospo

Chiara Rospo
 

UCB, Brussels, Belgium
 


She is Bionalytical Scientific Manager and Clinical Innovation lead at UCB Biopharma SRL (Brussels, Belgium). She received her MSc Degree in Chemistry from the University of Pavia in 1999. Afterwards, she spent ten years in different pharma companies and biotech (Pharmacia, GlaxoSmithKline, Cell Therapeutics) in the bioanalytical departments where she held roles of increasing responsibility. In 2009 she joined UCB Biopharma SRL as Head of Discovery Bioanalysis (Belgium site) and in 2015 she became Bioanalytical Scientific Manager. In addition to her role, she recently joined the clinical innovation team as Clinical Innovation Lead to set up and implement patient centric sampling strategy to allow decentralised clinical trials.

Simona Scarpella

Simona Scarpella
 

Waters Italy
 


She met the Mass Spectrometry during her thesis in Organic Chemistry at the University of Pavia and never stopped working in that field since then. She had the opportunity to work in several pharmaceutical companies in Analytical Department group and as a support to research group always using Mass Spectrometry. She started with Bracco in 1996 using an ion trap to characterise synthetic compounds, move then to Zambon in 1998 to coordinate different activities in both analytical research and development but spent about 10 years in the company that was Pharmacia &Upjohn at the begininning and now is Nerviano Medical Sciences. When in P&U she met the HRMS used mainly to support the impurity profile among many other activities. In 2004 she decided to change her view and move to work in Waters as High-Resolution Mass Spectrometry (HRMS) specialist supporting customers in different application areas (from Met ID, to ADC characterization through small molecule structural ID).

Debora Tagliacozzi

Debora Tagliacozzi
 

Menarini Ricerche S.p.A.
 


She is currently Head of DMPK & Bioanalytical Unit of Menarini Ricerche S.p.A. She has extensive experience as Senior Study Director / Principal Investigator in both preclinical and clinical bioanalytical chemistry according to GLP and GCP procedures and is a member of the European Bioanalytical Forum. She received her MSc in Chemistry from the University of Rome "La Sapienza" in 1997. She has spent her entire professional life in the bioanalytical field, with particular reference to the use of chromatographic systems with traditional detectors and mass spectrometers. She worked first at the "Bambino Gesù" pediatric hospital in Rome and then in Menarini Ricerche in a GLP and GCP regulated environment.

Franco Tagliaro

Franco Tagliaro
 

University of Verona, Verona, Italy
 


Full professor of Forensic Medicine and Science at the University of Verona and vice director of the Pharmacokinetics and Metabolomics Laboratory, IM Sechenov University, Moscow. Associate editor of "Medicine Science and The Law". Ad hoc consultant of UNDCP (United Nations International Drug Control Program, Vienna) and member of the International Panel of Forensic Experts of UNODC (United Nations Office on Drugs and Crime, Vienna). Publications: more than 200 articles in extenso in international or national journals and books with international and national publisher (H-index = 39).

Barbara Vaccarini

Barbara Vaccarini
 

Aptuit (Verona) Srl, an Evotec Company
 


Degree in Pharmaceutical Chemistry (CTF) and Certified as Pharmacist at Università degli Studi di Padova. She has more than 15 years of experience in the Pharmaceutical Industry performing different roles in different regulated environments. She started in GMP quality assurance in GlaxoSmithKline Manufacturing as a microbiological specialist and then as a filling expert acquiring knowledge of GMP regulations applied to the production of cephalosporin for injection in a sterile environment. After two years she moved to the Bioanalytical department of GlaxoSmithKline R&D where she worked in a GLP environment, moving then to GLP/GCP QA. She now has the role of Manager of GLP/GCP quality assurance in Aptuit, an Evotec Company, responsible for all Quality Assurance GLP and GCP activities. Her responsibilities range from assuring Test Facility Management of compliance with GLP/GCP principles to provide regulatory support to the Business operations, to manage the validation of computerized systems, host Client and Regulatory inspections, collect and trend quality metrics.

Registration

Please fill in the on-line registration form here and send a copy of the bank transfert by email to the SSPA2022 Secretariat at secretariat@sspaweb.com. Your registration will be confirmed only upon reception of the Proof of Payment.

Participants to the SSPA2022 can choose between three registration packages: an All Inclusive Registration (attendance in presence), a Basic Registration (attendance in presence) and a Virtual ticket (virtual meeting).

In the unfortunate case of a fresh outbreak of COVID19 pandemia, the SSPA2022 will be held as fully virtual event. Registered attendees who have opted for an All Inclusive or a Basic registration will be fully refunded in the case they decide to decline their attendance, or partially refunded in the case they opt for attending the virtual event. In the latter case the difference in price between the paid registration and the virtual ticket will be refunded.

ALL INCLUSIVE

  • Conference Tickets
  • Coffee breaks and meals
  • Abstract book
  • Social dinner
  • 3 nights accommodation§

€ 400

SCI/EFMC members
Before June 27 (*Prices inclusive VAT)
€ 440 After June 27 (*Prices inclusive VAT)

€ 440

Not SCI/EFMC members
Before June 27 (*Prices inclusive VAT)
€ 480 After June 27 (*Prices inclusive VAT)
§in a double/twin room at a three-star hotel located at a walking distance from the SSPA2022 venue (Single room supplement for 3 nights € 60)

BASIC

  • Conference Tickets
  • Coffee breaks and meals
  • Abstract book
  • Social dinner
  •  

€ 290

SCI/EFMC members
Before June 27 (*Prices inclusive VAT)
€ 330 After June 27 (*Prices inclusive VAT)

€ 330

Not SCI/EFMC members
Before June 27 (*Prices inclusive VAT)
€ 370 After June 27 (*Prices inclusive VAT)

VIRTUAL TICKET

  • Conference Tickets
  • Three-day access to lectures
  • Abstract book
  •  
     

€ 120

SCI/EFMC members
Before June 27 (*Prices inclusive VAT)
€ 140 After June 27 (*Prices inclusive VAT)

€ 140

Not SCI/EFMC members
Before June 27 (*Prices inclusive VAT)
€ 160 After June 27 (*Prices inclusive VAT)

Registration policy and fees All registrations will be accepted until September 4th, 2022. After this date, only basic and virtual will be accepted. Registration will close on September 13th, 2022.

GDPR The personal information we receive from participants will also be required after the School for statistical purposes and for the dispatch of information on relevant symposia/school in the future. If you do not wish your personal data to be published or distributed, please inform us when you register for the summer school.

Confirmation An e-mail confirming your registration will be sent to you upon reception of a pdf proof of bank trasnfer.

Cancellation must be submitted in writing to the SSPA 2022 Secretariat (secretariat@sspaweb.com). The policy regarding refund of the registration fee is as follows: For all inclusive registrations, cancellations received before September 4th, 2022 will not be charged by any fee but bank fee will be deducted. After September 4th, 2022 no refund will be made. For basic and virtual registrations, for cancellations received before September 13th, 2022 there will not be a cancellation charge (bank fee shall be deducted). After September 13th, 2022 no refund will be made.

Payment All payments should be made in Euro by bank transfer to:
Account holder: Società Chimica Italiana-SSPA
Bank address: DEUTSCHE BANK MILANO C 463, VIALE GIUSTINIANO 1
Iban Code: IT50N0310401603000000821734
Swift Code: DEUT IT M1463
Remittance have to be free of any bank charges to the organizers.

For extra-EU partecipants having troubles with payment by bank transfer a payment by credit card can be arranged upon request. To have it arranged please contact the SSPA2022 secretariat at secretariat@sspaweb.com

Proof of Payment must be submitted by e-mail (secretariat@sspaweb.com) at the time of registration. Please ensure that the name and company/University of each delegate is printed clearly to ensure that the payment will be correctly registered. The payment receipt and the attendance certificate will be sent to the participant by email at the completion of the School.

Insurance The Organizing Committee cannot accept any liability. Participants should make their own arrangements with respect to health and travel insurance.

Fellowships

The Divisione di Chimica Farmaceutica of the Società Chimica Italiana (Italian Chemical Society) grants 3 fellowships for the participation to SSPA2022. Fellowships, covering the registration fee and accomodation, are reserved to young members of the Divisione di Chimica Farmaceutica with no permanent position at their institution (PhD students, graduated fellows and post-doctoral fellows, RTDa, volunteers or young researchers from other public research bodies), born after 30 April 1987.
A Committee will carry out the selection on the basis of the candidate scientific CV and research project. More details are available here (in Italian).
Applicants are invited to send the CV, a motivation letter and the abstract of the research project, by e-mail, stating in the subject box “Candidatura Bando Borse di Studio SSPA 2022”, within April 30th, 2022.

Abstract submission

Italian and foreign Ph.D. students in the end phase of their Ph.D. project are kindly invited to orally present their work (20 minutes including discussion). Abstracts will be evaluated by the scientific committee prior acceptance. In the case the number of candidate presentations exceeds the number that can be accommodated in the program, a selection will be made on the basis of novelty, pertinence, and clarity. Abstracts for Ph.D. oral presentations must be submitted before June 23, 2022, according to the template given here.

The PhD students whose abstract has been accepted must complete their registration within the early registration date to have their presentation confirmed.

  • The abstract must be written in English and sent as e-mail attachment (word file) to secretariat@sspaweb.com
  • Maximum length is 5 pages
  • Please edit carefully your abstract before submitting it and pay attention to reference style
  • A letter from the PhD mentor stating the PhD status of the presenter and compliance with the requirment of being an experienced PhD student (from the 3rd year onwards) should be submitted together with the abstract
  • We remind you that the presenting author must register before abstract submission

 
Committees

Scientific committee

  • Manuela Bartolini, Chair (University of Bologna, IT)
  • Massimo Breda (Aptuit Verona, an Evotec company)
  • Marina Carini (University of Milan, IT)
  • Ersilia De Lorenzi (University of Pavia, IT)
  • Francesco Epifano (University of Chieti, IT)
  • Alberto Massarotti (University of Piemonte Orientale, IT)
  • Federica Pellati (University of Modena e Reggio Emilia, IT)
  • Roccaldo Sardella (University of Perugia, IT)
  •  

Local Organizing committee

  • Manuela Bartolini (University of Bologna, IT)
  • Lara Davani (University of Bologna, IT)
  • Serena Montanari (University of Bologna, IT)
  • Marina Naldi, Secretariat (University of Bologna, IT)
  •  

 
Sponsors

Previous editions

Summer Course on Pharmaceutical Analysis

Sept 26-27, 2007 (Island of Elba, IT)

Summer Course on Pharmaceutical Analysis

June 29-30, 2006 (Cogne, IT)

Summer Course on Pharmaceutical Analysis

Sept 29-30, 2005 (Rimini, IT)

Summer Course on Pharmaceutical Analysis

May 2, 2004 (Florence, IT)

Summer Course on Pharmaceutical Analysis

July 1-3, 2003 (Cogne, IT)

Summer Course on Pharmaceutical Analysis

June 10-13, 2002 (Island of Elba, IT)

Summer Course on Pharmaceutical Analysis

June 3-5, 2001 (Lipari, IT)

Summer Course on Pharmaceutical Analysis

Sept 30-Oct 3, 2000 (Island of Elba, IT)

Summer Course on Pharmaceutical Analysis

June 28-29, 1999 (Rome, IT)

Summer Course on Pharmaceutical Analysis

June 10-12, 1998 (Island of Elba, IT)

Summer Course on Pharmaceutical Analysis

Sept 15-16, 1997 (Island of Elba, IT)

Summer Course on Pharmaceutical Analysis

June 12-14, 1996 (Island of Elba, IT)